Atypical type A thymoma component identified by pulmonary metastasectomy 11 years after surgery of type AB thymoma

Atypical type A thymoma component identified by pulmonary metastasectomy 11 years after surgery of type AB thymoma

Blog Article

Atypical type A thymomas exhibit more aggressive features than conventional type A thymomas.Type AB thymomas rarely have atypical type A components.We report a rare case of type AB thymoma with an atypical type A component, that was identified after pulmonary metastasectomy 11 years after the primary surgery and long-term follow-up after recurrence.

A 61-year-old female underwent extended thymectomy hemi procharger for an anterior mediastinal tumor 11 years prior and was diagnosed with type AB thymoma (Masaoka stage II).Five years ago, follow-up computed tomography showed well-circumscribed pulmonary nodules up to 1.0 cm in both lungs.

All the pulmonary nodules grew slowly; however, one of the nodules grew to 1.6 cm, and thoracoscopic wedge resection was performed for diagnosis.Pathologically, the pulmonary nodule was consisted of type A thymoma component.

Conventional type AB thymomas are usually locally aggressive neoplasms; thus, we reviewed the tissue slides of primary thymomas.Histologically, cytological atypia, hypercellularity, and increased mitosis are observed in the type A component.Consequently, the diagnosis was revised to a type AB thymoma with an atypical type A component.

The pulmonary nodule exhibited the same atypical type A features.Pulmonary metastasectomy was billionaire boys club discount code 2023 performed two more times as volume-reduction surgery.The residual metastasis was located only in the lung with slow growth, 4 years after the first pulmonary resection; therefore, we followed up as an outpatient without treatment.